Resources

Shared research group resources and outputs

PULSAR

PULSAR (an acronym of Protein Unfolding for Ligand Stabilisation and Ranking, formerly ionMS) is specialised software for the processing and analysis of ion mobility-mass spectrometry data. PULSAR can import data directly from Waters RAW files, annotated with appropriate meta data, and enables:

  • Viewing of ion mobility mobiligrams
  • Basic deconvolution and charge state assignment for native mass spectra
  • Calculation of calibrations for travelling-wave ion mobility collision cross section (CCS) measurements
  • Automated CCS measurements of protein and small molecule ions
  • Extraction of mobiligram regions for ion mobility-based separation
  • Enhanced analysis of gas-phase hydrogen-deuterium exchange experiments
  • Generation of gas-phase protein unfolding plots
  • Comprehensive analysis and calculation of gas phase behaviour and stability of ions

Presently PULSAR is available from its Oxford University webpage and is free for academic use.